Facteur de Transcription ICBP90
Unoki M, Kelly JD, Neal DE, Ponder BA, Nakamura Y, Hamamoto R. UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer. 2009 Jul 7;101(1):98-105.
Fang Z, Xing F, Bronner C, Teng Z, Guo Z.ICBP90 mediates the ERK1/2 signaling to regulate the proliferation of Jurkat T cells. Cell Immunol. 2009;257(1-2):80-7.
Li XL, Meng QH, Fan SJ.Adenovirus-mediated expression of UHRF1 reduces the radiosensitivity of cervical cancer HeLa cells to gamma-irradiation. Acta Pharmacol Sin. 2009 Apr;30(4):458-66
Hashimoto H, Horton JR, Zhang X, Cheng X.UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications. Epigenetics. 2009 Jan;4(1):8-14.
Kim JK, Estève PO, Jacobsen SE, Pradhan S.UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells. Nucleic Acids Res. 2009 Feb;37(2):493-505.
Delagoutte B, Lallous N, Birck C, Oudet P, Samama JP.Expression, purification, crystallization and preliminary crystallographic study of the SRA domain of the human UHRF1 protein. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Oct 1;64(Pt 10):922-5.
Arita K, Ariyoshi M, Tochio H, Nakamura Y, Shirakawa M.Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature. 2008 Oct 9;455(7214):818-21.
Avvakumov GV, Walker JR, Xue S, Li Y, Duan S, Bronner C, Arrowsmith CH, Dhe-Paganon S.Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature. 2008 Oct 9;455(7214):822-5.
Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X.The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature. 2008 Oct 9;455(7214):826-9.
Mistry H, Gibson L, Yun JW, Sarras H, Tamblyn L, McPherson JP.Interplay between Np95 and Eme1 in the DNA damage response. Biochem Biophys Res Commun. 2008 Oct 24;375(3):321-5
Papait R, Pistore C, Grazini U, Babbio F, Cogliati S, Pecoraro D, Brino L, Morand AL, Dechampesme AM, Spada F, Leonhardt H, McBlane F, Oudet P, Bonapace IM.The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin. Mol Biol Cell. 2008 Aug;19(8):3554-63.
Ooi SK, Bestor TH.Cytosine methylation: remaining faithful. Curr Biol. 2008 Feb 26;18(4):R174-6.
Unoki M, Bronner C, Mousli M.A concern regarding the current confusion with the human homolog of mouse Np95, ICBP90/UHRF1. Radiat Res. 2008 Feb;169(2):240-4.
Brunet J, Pfaff AW, Abidi A, Unoki M, Nakamura Y, Guinard M, Klein JP, Candolfi E, Mousli M.Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation. Cell Microbiol. 2008 Apr;10(4):908-20.
Sharif J, Muto M, Takebayashi S, Suetake I, Iwamatsu A, Endo TA, Shinga J, Mizutani-Koseki Y, Toyoda T, Okamura K, Tajima S, Mitsuya K, Okano M, Koseki H.The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature. 2007 Dec 6;450(7171):908-12.
Karagianni P, Amazit L, Qin J, Wong J.ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation. Mol Cell Biol. 2008 Jan;28(2):705-17.
Achour M, Jacq X, Rondé P, Alhosin M, Charlot C, Chataigneau T, Jeanblanc M, Macaluso M, Giordano A, Hughes AD, Schini- Kerth VB, Bronner C.The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression. Oncogene. 2008 Apr 3;27(15):2187-97.
Macaluso M, Montanari M, Noto PB, Gregorio V, Bronner C, Giordano A.Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer. Cancer Res. 2007 Aug 15;67(16):7731-7.
Bostick M, Kim JK, Estève PO, Clark A, Pradhan S, Jacobsen SE.UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science. 2007 Sep 21;317(5845):1760-4
Bronner C, Achour M, Arima Y, Chataigneau T, Saya H, Schini-Kerth VB. The UHRF family: oncogenes that are drugable targets for cancer therapy in the near future? Pharmacol Ther. 2007 Sep;115(3):419-34.
Sadler KC, Krahn KN, Gaur NA, Ukomadu C.Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1570-5.
Papait R, Pistore C, Negri D, Pecoraro D, Cantarini L, Bonapace IM.Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing. Mol Biol Cell. 2007 Mar;18(3):1098-106.
Muto M, Fujimori A, Nenoi M, Daino K, Matsuda Y, Kuroiwa A, Kubo E, Kanari Y, Utsuno M, Tsuji H, Ukai H, Mita K, Takahagi M, Tatsumi K.Isolation and Characterization of a Novel Human Radiosusceptibility Gene, NP95. Radiat Res. 2006 Nov;166 (5):723-33.
Un F, Qi C, Prosser M, Wang N, Zhou B, Bronner C, Yen Y. Modulating ICBP90 to suppress human ribonucleotide reductase M2 induction restores sensitivity to hydroxyurea cytotoxicity. Anticancer Res. 2006 Jul-Aug;26(4B):2761-7.
Lorenzato M, CaudroyS, Bronner C, Evrard G, Simon M, Durlach A, Birembaut P, Clavel
C. Cell cycle and/or proliferation markers: what is the best method to discriminate cervical high-grade lesions? Hum Pathol. 2005 Oct;36(10):1101-7.
Jeanblanc M, Mousli M, Hopfner R, Bathami K, Martinet N, Abbady AQ, Siffert JC, Mathieu E, Muller CD, Bronner C. The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle. Oncogene. 2005 Nov 10;24(49):7337-45.
Abbady AQ, Bronner C, Bathami K, Muller CD, Jeanblanc M, Mathieu E, Klein JP, Candolfi E, Mousli M. TCR pathway involves ICBP90 gene down-regulation via E2F binding sites. Biochem Pharmacol. 2005 Aug 15;70(4):570-9.
Bronner C, Trotzier MA, Filhol O, Cochet C, Rochette-Egly C, Scholler-Guinard M, Klein JP, Mousli M. The antiapoptotic protein ICBP90 is a target for protein kinase 2. Ann N Y Acad Sci. 2004 Dec;1030:355-60.
Unoki M, Nishidate T, Nakamura Y. ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene. 2004 Oct 7;23(46):7601-10.
Trotzier MA, Bronner C, Bathami K, Mathieu E, Abbady AQ, Jeanblanc M, Muller CD, Rochette-Egly C, Mousli M. Phosphorylation of ICBP90 by protein kinase A enhances topoisomerase IIalpha expression. Biochem Biophys Res Commun. 2004 Jun 25;319(2):590-5
Hopfner R, Mousli M, Jeltsch JM, Voulgaris A, Lutz Y, Marin C, Bellocq JP, Oudet P and Bronner C. ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression. Cancer Res 60, 121-128, 2000.
Hopfner R, Mousli M, Garnier JM, Redon R, Du Manoir S, Chatton B, Ghyselinck N, Oudet P and Bronner C. Genomic structure and chromosomal mapping of the gene coding for ICBP90, a protein involved in the regulation of the topoisomerase IIalpha gene expression. Gene
266, 15-23, 2001.
Bronner C, Hopfner R, and Mousli M. Transcriptional Regulation of the Human Topoisomerase IIalpha gene. Anticancer Res 22 (2A), 605-612, 2002.
Hopfner R, Mousli M, Oudet P and Bronner C. Overexpression of ICBP90, a novel CCAAT-binding protein, overcomes cell contact inhibition by forcing topoisomerase IIalpha expression. Anticancer Res 22(6A), 3165-3170, 2002.
Mousli M, Hopfner R, Abbady AQ, Monte D, Jeanblanc M, Oudet P, Louis B, Bronner C.
ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells. Br J Cancer 89 (1), 120-127, 2003.
Abbady AQ, Bronner C, Trotzier MA, Hopfner R, Bathami K, Muller CD, Jeanblanc M and Mousli M. ICBP90 expression is downregulated in apoptosis-induced jurkat cells. Ann. NY Acad. Sci. 1010, 300-303, 2003.
Arima Y, Hirota T, Bronner C, Mousli M, Fujiwara T, Niwa S-I, Ishikawa H, Saya H . Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition. Genes to Cells 9 (2), 131-142, 2004.